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Centrosome function
during stem cell division: the devil is in the details.

Polyhomeotic
tumor suppression activity through repression of Notch signaling.
In colaboration with
the Cavalli lab

Spindle alignment achieved without rotation after first cell cycle in
embryonic neuroblasts.

Review on biased segregation of DNA
and centrosomes.

Our
goal is to
understand the mechanisms of cell
division. We apply a multidisciplinary approach that combines
genetics, molecular biology and advanced in
vivo
microscopy.
We use Drosophila as well as
cultured
cells derived from vertebrates as model
systems.
Current
on-going projects
include the study of the
mechanisms
of spindle assembly, the characterisation of
new centrosomal proteins and the modelling of
cancer
in Drosophila.
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